The Long-Term Impact of Measles: How Vaccines Prevent Deadly Outcomes
Measles vaccines have played a crucial role in preventing disease, long-term immune damage, and deadly outbreaks. A recent cohort study in the UK highlighted the impact and longevity of measles-induced immune suppression, revealing how the virus leaves children vulnerable to other diseases for years.
Measles vaccines were introduced 50 years ago and have led to significant reductions in child morbidity and mortality. Despite these successes, many countries still face challenges in meeting vaccination targets, resulting in continued measles-related deaths each year. Recent studies in Science and Science Immunology have shown the long-term damage caused by the measles virus, creating a form of immune amnesia that increases the risk of illness from other diseases in children.
Children recovering from measles may experience months to years of immune vulnerability, leading to an overall increase in childhood infectious disease mortality. Complications from measles can range from hospitalizations to permanent hearing loss and neurological issues. The recent measles outbreak in the US has raised concerns about the long-term health effects of the disease, especially in young children.
Measles pneumonia, a common complication, can be fatal in young children, highlighting the seriousness of the virus. Studies in Switzerland and Germany have reported increased rehospitalization rates and relative risks for infectious diseases in children post-measles infection.
A retrospective study in Italy aimed to identify risk factors for severe measles outcomes, such as long-lasting sequelae, intensive care needs, or death, emphasizing the importance of understanding and addressing the impact of measles on public health.
Overall, the research shows that measles not only directly affects various body systems but also suppresses the immune system, making individuals vulnerable to a range of infectious diseases. Vaccination remains the most effective way to prevent severe outcomes and combat the resurgence of measles in communities worldwide.
